【2024年版】うつ病治療のSR&MA7選

うつ病に関するSR&MAの中からこれは最低限押さえておきたいものを厳選しました。

Furukawa TA, Shinohara K, Sahker E, et al. Initial treatment choices to achieve sustained response in major depression: a systematic review and network meta-analysis. World Psychiatry. 2021;20(3):387-396. doi:10.1002/wps.20906 https://pubmed.ncbi.nlm.nih.gov/34505365/

→初期治療から心理療法を提供することが長期的にベスト

Cuijpers P, Quero S, Noma H, et al. Psychotherapies for depression: a network meta-analysis covering efficacy, acceptability and long-term outcomes of all main treatment types. World Psychiatry. 2021;20(2):283-293. doi:10.1002/wps.20860 https://pubmed.ncbi.nlm.nih.gov/34002502/

→うつ病治療の心理療法の網羅的NMA

Furukawa TA, Suganuma A, Ostinelli EG, et al. Dismantling, optimising, and personalising internet cognitive behavioural therapy for depression: a systematic review and component network meta-analysis using individual participant data. Lancet Psychiatry. 2021;8(6):500-511. doi:10.1016/S2215-0366(21)00077-8 https://pubmed.ncbi.nlm.nih.gov/33957075/

→うつ病用のインターネットCBTのどの要素が有効かを検討したcNMA

Cipriani A, Furukawa TA, Salanti G, et al. Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis. Lancet. 2018;391(10128):1357-1366. doi:10.1016/S0140-6736(17)32802-7 https://pubmed.ncbi.nlm.nih.gov/29477251/

→抗うつ薬の網羅的NMA

Furukawa TA, Cipriani A, Cowen PJ, Leucht S, Egger M, Salanti G. Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis. Lancet Psychiatry. 2019;6(7):601-609. doi:10.1016/S2215-0366(19)30217-2 https://pubmed.ncbi.nlm.nih.gov/31178367/

→抗うつ薬は低用量から中等量で使うのが良さそうという用量反応メタアナリシス

Kato M, Hori H, Inoue T, et al. Discontinuation of antidepressants after remission with antidepressant medication in major depressive disorder: a systematic review and meta-analysis. Mol Psychiatry. 2021;26(1):118-133. doi:10.1038/s41380-020-0843-0 https://pubmed.ncbi.nlm.nih.gov/32704061/

→うつ病寛解後も抗うつ薬を続けたほうが寛解維持率あがる

Breedvelt JJF, Warren FC, Segal Z, Kuyken W, Bockting CL. Continuation of Antidepressants vs Sequential Psychological Interventions to Prevent Relapse in Depression: An Individual Participant Data Meta-analysis. JAMA Psychiatry. 2021;78(8):868-875. doi:10.1001/jamapsychiatry.2021.0823 https://pubmed.ncbi.nlm.nih.gov/34009273/

→うつ病寛解後に心理療法をしっかりすれば抗うつ薬減らしても寛解率は維持される


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